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Aging and Senescence in Canine Testes

6 May 2019

Abstract excerpt

Senescent cells accumulate with age but tissue-based studies of senescent cells are limited to selected organs from humans, mice, and primates. Cell culture and xenograft studies have indicated that senescent cells in the microenvironment may play a role in tumor proliferation via paracrine activities. Dogs develop age-related conditions, including in the testis, but cellular senescence has not been confirmed. We...

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PMID: 31060479
DOI: 10.1177/0300985819843683

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