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Article

Homeostasis of the sebaceous gland and mechanisms of acne pathogenesis

6 May 2019

Abstract excerpt

BACKGROUND: Sebaceous glands (SGs) are appendages of mammalian skin that produce a mixture of lipids known as sebum. Acne vulgaris is an exceptionally common skin condition, characterized by elevated sebum production, altered sebum composition, and the formation of infundibular cysts, called comedones. Comedo-associated SGs are atrophic, suggesting that comedo formation involves abnormal differentiation of...

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PMID: 31056753
DOI: 10.1111/bjd.17981

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