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Article

The Inflammatory Basis of Acne Pathogenesis.

Dermatology (Basel, Switzerland) - 1 Jan 2026

Han Shuang, Ding Zonghuang, Zheng Junfeng, Bai Hui, Xu Hong, Ren Xiaoling, Li Min

Abstract excerpt

BACKGROUND: Acne is a common inflammatory and genetically influenced skin disease. Previous genome-wide association studies and epigenome-wide association studies have demonstrated that genetic factors constitute an important basis for acne susceptibility, while recurrent and persistent local inflammatory responses contribute to its chronic and relapsing nature. SUMMARY: Infection with Cutibacterium acnes,...

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Acne Vulgaris
Inflammasomes
Inflammation
Interleukin-6
NLR Family, Pyrin Domain-Containing 3 Protein

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Signal Transduction

STAT3 Transcription Factor

Toll-Like Receptors

Source

Identifiers

PMID: 41911087
DOI: 10.1159/000551553

Genes

NLRP3
STAT3

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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