Article
High fat programming of beta-cell failure.
Advances in experimental medicine and biology - 1 Jan 2010
Cerf Marlon E
Abstract excerpt
High saturated fat intake contributes to insulin resistance, beta-cell failure, and type 2 diabetes. Developmental programming refers to a stimulus or insult during critical periods of life which includes fetal and subsequent early neonatal life. Programming alters offspring physiology and metabolism with both immediate and lasting consequences. Maternal nutrition in gestation and lactation shapes offspring...
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