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Article

CD34 defines melanocyte stem cell subpopulations with distinct regenerative properties

24 Apr 2019

Abstract excerpt

Melanocyte stem cells (McSCs) are the undifferentiated melanocytic cells of the mammalian hair follicle (HF) responsible for recurrent generation of a large number of differentiated melanocytes during each HF cycle. HF McSCs reside in both the CD34+ bulge/lower permanent portion (LPP) and the CD34- secondary hair germ (SHG) regions of the HF during telogen. Using Dct-H2BGFP mice, we separate bulge/LPP and SHG...

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PMID: 31017901
DOI: 10.1371/journal.pgen.1008034

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