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Targeting telomerase for cancer therapeutics

29 Jan 2008

Abstract excerpt

One of the hallmarks of advanced malignancies is continuous cell growth and this almost universally correlates with the reactivation of telomerase. Although there is still much we do not understand about the regulation of telomerase, it remains a very attractive and novel target for cancer therapeutics. Several clinical trials have been initiated, and in this review we highlight some of the most promising...

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PMID: 18231105
DOI: 10.1038/sj.bjc.6604209

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