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Article

MicroRNA expression profile in retina and choroid in oxygen-induced retinopathy model

12 Jun 2019

Abstract excerpt

BACKGROUND: Ischemic retinopathies (IRs) are leading causes of visual impairment. They are characterized by an initial phase of microvascular degeneration and a second phase of aberrant pre-retinal neovascularization (NV). microRNAs (miRNAs) regulate gene expression, and a number play a role in normal and pathological NV. But, post-transcriptional modulation of miRNAs in the eye during the development of IRs has...

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PMID: 31188886
DOI: 10.1371/journal.pone.0218282

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