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Exosomal miR-135a-5p promotes neovascularization via targeting SIRT1 in diabetic retinopathy

2022-07-14

Abstract excerpt

<h4>Background: </h4> Diabetic retinopathy (DR) is one of the most serious microvascular complications of diabetes mellitus. Retinal neovascularization （RNV) under the continuous influence of hyperglycemia is the main cause of blindness in DR patients, but the mechanism of neovascularization has not been fully elucidated yet. In this study, we investigated the effect of exosomes secreted by human retinal pigmented...

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Literature Corpus work
1a52329d-f77b-5e4b-b1d4-dd3b9b92c900
DOI
10.21203/rs.3.rs-1827034/v1
Open publication

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Exosomal miR-135a-5p promotes neovascularization via targeting SIRT1 in diabetic retinopathyDOI 10.21203/rs.3.rs-1827034/v1
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