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Article

Differential regulation of macropinocytosis by Abi1/Hssh3bp1 isoforms.

PloS one - 10 May 2010

Dubielecka Patrycja M, Cui Ping, Xiong Xiaoling, Hossain Sajjad, Heck Susanne, Angelov Lyudmil, Kotula Leszek

Abstract excerpt

BACKGROUND: Macropinocytosis, which is a constitutive cellular process of fluid and macromolecule uptake, is regulated by actin cytoskeleton rearrangements near the plasma membrane. Activation of Rac1, which is proposed to act upstream of the actin polymerization regulatory Wave 2 complex, has been found to correlate with enhanced macropinocytosis. One of the components of the Wave 2 complex is Abi1. Multiple,...

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Identifiers

PMID: 20479892
DOI: 10.1371/journal.pone.0010430
PMCID: PMC2866655

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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