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Article

Musashi-1 Enhances Glioblastoma Migration by Promoting ICAM1 Translation

6 Apr 2019

Abstract excerpt

Glioblastoma multiforme (GBM) is a lethal brain tumor with a mean survival time of 1 year. One major reason for therapeutic failure is that GBM cells have an extraordinary capacity to invade normal brain tissue beyond the surgical margin, accounting for the lack of treatment efficacy. GBM cells that can infiltrate into the healthy brain possess tumor properties of stemness and invasion, and previous studies...

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PMID: 30959276
DOI: 10.1016/j.neo.2019.02.006

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