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Quantitative Size-Based Analysis of Tumor Spheroids and Responses to Therapeutics

1 Apr 2019

Abstract excerpt

Drug resistance remains a major clinical problem despite advances in targeted therapies. In recent years, methods to culture cancer cells in three-dimensional (3D) environments to better mimic native tumors have gained increasing popularity. Nevertheless, unlike traditional two-dimensional (2D) cell cultures, analysis of 3D cultures is not straightforward. Most biochemical assays developed for 2D cultures have to...

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PMID: 30958703
DOI: 10.1089/adt.2018.895

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