hicap: In Silico Serotyping of the Haemophilus influenzae Capsule Locus

Abstract excerpt

Haemophilus influenzae exclusively colonizes the human nasopharynx and can cause a variety of respiratory infections as well as invasive diseases, including meningitis and sepsis. A key virulence determinant of H. influenzae is the polysaccharide capsule, of which six serotypes are known, each encoded by a distinct variation of the capsule biosynthesis locus ( cap -a to cap -f).

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