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Development and implementation of a core genome multilocus sequence typing scheme for Haemophilus influenzae.

Microbial genomics - 1 Aug 2024

Krisna Made Ananda, Jolley Keith A, Monteith William, Boubour Alexandra, Hamers Raph L, Brueggemann Angela B, Harrison Odile B, Maiden Martin C J

Abstract excerpt

Haemophilus influenzae is part of the human nasopharyngeal microbiota and a pathogen causing invasive disease. The extensive genetic diversity observed in H. influenzae necessitates discriminatory analytical approaches to evaluate its population structure. This study developed a core genome multilocus sequence typing (cgMLST) scheme for H. influenzae using pangenome analysis tools and validated the cgMLST scheme...

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Identifiers

PMID: 39120932
DOI: 10.1099/mgen.0.001281
PMCID: PMC11315579

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