Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Diazaquinomycin Biosynthetic Gene Clusters from Marine and Freshwater Actinomycetes

21 Mar 2019

Abstract excerpt

Tuberculosis is an infectious disease of global concern. Members of the diazaquinomycin (DAQ) class of natural products have shown potent and selective activity against drug-resistant Mycobacterium tuberculosis. However, poor solubility has prevented further development of this compound class. Understanding DAQ biosynthesis may provide a viable route for the generation of derivatives with improved properties. We...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Genomics and Phylogenetic Studies
Share to Microbial Natural Products and Biosynthesis
Share to Mycobacterium research and diagnosis

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 30896942
DOI: 10.1021/acs.jnatprod.8b01028

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 23 Oct 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Diazaquinomycin Biosynthetic Gene Clusters from Marine and Freshwater ActinomycetesPMID 30896942Read ↗

Comparative genomics of actinomycetes with a focus on natural product biosynthetic genesSemantic proximity Read ↗

Identification of the Actinomycin D Biosynthetic Pathway from Marine-Derived Streptomyces costaricanus SCSIO ZS0073Semantic proximity Read ↗

Complete Genome of Micromonospora sp. Strain B006 Reveals Biosynthetic Potential of a Lake Michigan ActinomyceteSemantic proximity Read ↗

Microbial bioprospecting for benzoxazolinate-like molecules: unleashing the potential of genome miningSemantic proximity Read ↗

Global analysis of biosynthetic gene clusters reveals vast potential of secondary metabolite production in Penicillium species.Semantic proximity Read ↗

Diversity and taxonomic distribution of bacterial biosynthetic gene clusters predicted to produce compounds with therapeutically relevant bioactivitiesSemantic proximity Read ↗

Mining biosynthetic gene clusters in Paenibacillus genomes to discover novel antibioticsSemantic proximity Read ↗

Pattern-based genome mining guides discovery of the antibiotic indanopyrrole A from a marine streptomyceteSemantic proximity Read ↗

Pattern-Based Genome Mining Guides Discovery of the Antibiotic Indanopyrrole A from a Marine StreptomyceteSemantic proximity Read ↗

Genome mining of biosynthetic and chemotherapeutic gene clusters in Streptomyces bacteriaSemantic proximity Read ↗

p-Aminophenylalanine Involved in the Biosynthesis of Antitumor Dnacin B1 for Quinone Moiety Formation.Semantic proximity Read ↗

Characterization and engineering of Streptomyces griseofuscus DSM 40191 as a potential host for heterologous expression of biosynthetic gene clusters.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.