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Enhanced Autophagy Contributes to Reduced Viral Infection in Black Flying Fox Cells

14 Mar 2019

Abstract excerpt

Bats are increasingly implicated as hosts of highly pathogenic viruses. The underlying virus⁻host interactions and cellular mechanisms that promote co-existence remain ill-defined, but physiological traits such as flight and longevity are proposed to drive these adaptations. Autophagy is a cellular homeostatic process that regulates ageing, metabolism, and intrinsic immune defense. We quantified basal and...

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PMID: 30875748
DOI: 10.3390/v11030260

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