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Article

Viruses and autophagy

14 Sept 2009

Abstract excerpt

Autophagy is an evolutionarily conserved intracellular process by which bulk cytoplasm is enveloped inside a double-membraned vesicle and shuttled to lysosomes for degradation. Within the last 15 years, the genes necessary for the execution of autophagy have been identified and the number of tools for studying this process has grown. Autophagy is essential for tissue homeostasis and development and defective...

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PMID: 19750559
DOI: 10.1002/rmv.630

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