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Autophagy-Virus Interplay: From Cell Biology to Human Disease

19 Nov 2018

Abstract excerpt

Autophagy is a highly conserved intracellular degradation process that targets protein aggregates and damaged organelles. Autophagy is also implicated in numerous viral infections, including human immunodeficiency virus-1 (HIV-1), influenza A (IAV) and herpes simplex virus-1 (HSV-1). Depending on the virus, autophagy can restrict or promote viral replication, and play key roles in modulating inflammation and cell...

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PMID: 30510929
DOI: 10.3389/fcell.2018.00155

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