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Article

Single-cell RNA sequencing of lung adenocarcinoma reveals heterogeneity of immune response–related genes

20 Feb 2019

Abstract excerpt

Immunotherapy has emerged as a promising approach to treat cancer. However, partial responses across multiple clinical trials support the significance of characterizing intertumor and intratumor heterogeneity to achieve better clinical results and as potential tools in selecting patients for different types of cancer immunotherapies. Yet, the type of heterogeneity that informs clinical outcome and patient...

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PMID: 30821712
DOI: 10.1172/jci.insight.121387

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