Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Primary closed angle glaucoma in the Basset Hound: Genetic investigations using genome-wide association and RNA sequencing strategies.

Molecular vision - 1 Jan 2019

Oliver James A C, Ricketts Sally L, Kuehn Markus H, Mellersh Cathryn S

Abstract excerpt

Purpose: To investigate the genetic basis of primary closed angle glaucoma (PCAG) in European Basset Hounds using genome-wide association and RNA sequencing strategies. Methods: DNA samples from 119 European Basset Hounds were genotyped on the 170 K SNP CanineHD BeadChip array (Illumina) comprising 37 with normal iridocorneal angles (controls), 57 with pectinate ligament abnormality (PLA cases), and 25 with PCAG...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Dog Diseases
Share to Europe
Share to Eye Proteins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene Ontology

Share to Glaucoma, Angle-Closure

Share to Molecular Sequence Annotation

Share to Muscle Proteins

Share to Sequence Analysis, RNA

Source

Open in PubMed Open full text

Identifiers

PMID: 30820145
PMCID: PMC6377385

Genes

NEB

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Primary closed angle glaucoma in the Basset Hound: Genetic investigations using genome-wide association and RNA sequencing strategies.PMID 30820145Read ↗

Variants in Nebulin (NEB) Are Linked to the Development of Familial Primary Angle Closure Glaucoma in Basset Hounds.Semantic proximity Read ↗

Identification of genetic loci associated with primary angle-closure glaucoma in the basset hound.Semantic proximity Read ↗

Genome-wide association study identifies a novel canine glaucoma locus.Semantic proximity Read ↗

A genome-wide association study to investigate genetic loci associated with primary glaucoma in American Cocker Spaniels.Semantic proximity Read ↗

Ocular morphologic traits in the American Cocker Spaniel may confer primary angle closure glaucoma susceptibilitySemantic proximity Read ↗

Ocular Morphologic Traits in the American Cocker Spaniel May Confer Primary Angle Closure Glaucoma SusceptibilitySemantic proximity Read ↗

Mapping of the disease locus and identification of ADAMTS10 as a candidate gene in a canine model of primary open angle glaucoma.Semantic proximity Read ↗

Dogs and humans share a common susceptibility gene SRBD1 for glaucoma risk.Semantic proximity Read ↗

Identification of putative SNPs in progressive retinal atrophy affected Canis lupus familiaris using exome sequencing.Semantic proximity Read ↗

Elucidating the genetic basis of canine progressive retinal atrophies in several breeds of dogSemantic proximity Read ↗

Arginine to glutamine mutation in olfactomedin like 3 ( <i>OLFML3</i> ) is a candidate for severe goniodysgenesis and glaucoma in the Border Collie dog breedSemantic proximity Read ↗

A Novel Genome-Wide Association Study Approach Using Genotyping by Exome Sequencing Leads to the Identification of a Primary Open Angle Glaucoma Associated Inversion Disrupting ADAMTS17.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.