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Article

Pathomechanisms of Altered Wound Healing in Recessive Dystrophic Epidermolysis Bullosa.

The American journal of pathology - 1 Jul 2017

Cianfarani Francesca, Zambruno Giovanna, Castiglia Daniele, Odorisio Teresa

Abstract excerpt

Individuals with recessive dystrophic epidermolysis bullosa (RDEB), a rare genetic skin disease, carry mutations in the COL7A1 gene that codes for type VII collagen, an extracellular matrix component of the basement membrane zone forming the anchoring fibrils. As a consequence, RDEB individuals manifest unremitting skin blistering that evolves into chronic wounds, inflammation, and fibrosis. These features play a...

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Identifiers

PMID: 28460207
DOI: 10.1016/j.ajpath.2017.03.003

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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