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Article

Protein profiling of osteosarcoma tissue and soft callus unveils activation of the unfolded protein response pathway

28 Feb 2019

Abstract excerpt

Oncogenic drivers of osteosarcoma remain controversial due to the complexity of the genomic background of the disease. There are limited novel therapeutic options, and the survival rate of patients with osteosarcoma has not improved in decades. Genomic instability leads to complexity in various pathways, which is potentially revealed at the protein level. Therefore, the present study aimed to identify the...

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PMID: 30816440
DOI: 10.3892/ijo.2019.4737

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