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Identification of potential crucial genes and key pathways in osteosarcoma

14 Jul 2020

Abstract excerpt

BACKGROUND: The aim of this study is to identify the potential pathogenic and metastasis-related differentially expressed genes (DEGs) in osteosarcoma through bioinformatic analysis of Gene Expression Omnibus (GEO) database. RESULTS: Gene expression profiles of GSE14359, GSE16088, and GSE33383, in total 112 osteosarcoma tissue samples and 7 osteoblasts, were analyzed. Seventy-four normal-primary DEGs (NPDEGs) and...

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PMID: 32665038
DOI: 10.1186/s41065-020-00142-0

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