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Article

Targeting long non-coding RNA PVT1/TGF-β/Smad by p53 prevents glioma progression

11 Mar 2022

Abstract excerpt

Glioma is a primary intracranial malignant tumor with poor prognosis, and its pathogenesis is unclear. This study discussed the impact of p53/lncRNA plasmacytoma variant translocation 1 (lncRNA PVT1)/transforming growth factor beta (TGF-β)/Smad axis on the biological characteristics of glioma. Glioma and normal tissues were collected, in which relative lncRNA PVT1 and p53 expression was assessed. Pearson’s...

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PMID: 35275031
DOI: 10.1080/15384047.2022.2042160

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