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Article

LncRNA PVT1 Regulates Chondrocyte Apoptosis in Osteoarthritis by Acting as a Sponge for miR-488-3p

18 May 2017

Abstract excerpt

Long noncoding RNAs (lncRNAs) have been known to be involved in multiple diverse diseases, including osteoarthritis (OA). The present study aims at exploring the biological role of lncRNA plasmacytoma variant translocation 1 (PVT1) in OA and the underlying mechanism. Results showed that the expression of PVT1 was upregulated in OA chondrocytes compared with normal chondrocytes, silencing PVT1 inhibited the...

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PMID: 28520497
DOI: 10.1089/dna.2017.3678

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LncRNA PVT1 Regulates Chondrocyte Apoptosis in Osteoarthritis by Acting as a Sponge for miR-488-3pPMID 28520497Read ↗

Long Non-coding RNA PVT1 Promotes Chondrocyte Extracellular Matrix Degradation by Acting as a Sponge for miR-140 in IL-1β-stimulated ChondrocytesSemantic proximity Read ↗

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