Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Human trophoblast requires galectin-3 for cell migration and invasion

14 Feb 2019

Abstract excerpt

Abstract Invasive extravillous cytotrophoblast of the human placenta expresses galectins-1, -3, and -8 in vivo and in vitro. This study aimed to investigate the potential role of galectin-3 in cell migration and invasion, using recombinant human galectin-3 (rhgalectin-3), small molecule galectin inhibitor I47, and galectin-3 silencing. HTR-8/SVneo cell migration was stimulated by rhgalectin-3 and reduced by I47,...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Galectins and Cancer Biology
Share to Peptidase Inhibition and Analysis
Share to Signaling Pathways in Disease

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 30765738
DOI: 10.1038/s41598-018-38374-w

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Human trophoblast requires galectin-3 for cell migration and invasionPMID 30765738Read ↗

REVIEW ARTICLE: Governing the Invasive Trophoblast: Current Aspects on Intra‐ and Extracellular RegulationSemantic proximity Read ↗

Galectin-1 influences trophoblast immune evasion and emerges as a predictive factor for the outcome of pregnancySemantic proximity Read ↗

Aquaporin 3 promotes human extravillous trophoblast migration and invasionSemantic proximity Read ↗

Critical growth factors and signalling pathways controlling human trophoblast invasionSemantic proximity Read ↗

Galectin-3 deficiency in pregnancy increases the risk of fetal growth restriction (FGR) via placental insufficiencySemantic proximity Read ↗

Snail mediates GDF-8-stimulated human extravillous trophoblast cell invasion by upregulating MMP2 expressionSemantic proximity Read ↗

Identification of Novel Trophoblast Invasion-Related Genes: Heme Oxygenase-1 Controls Motility via Peroxisome Proliferator-Activated Receptor γSemantic proximity Read ↗

Galectins: Double-edged Swords in the Cross-roads of Pregnancy Complications and Female Reproductive Tract Inflammation and NeoplasiaSemantic proximity Read ↗

Investigation of human trophoblast invasion in vitroSemantic proximity Read ↗

Wnt-Dependent T-Cell Factor-4 Controls Human Etravillous Trophoblast MotilitySemantic proximity Read ↗

Galectins: Important Regulators in Normal and Pathologic PregnanciesSemantic proximity Read ↗

Neuregulin 1-mediated ErbB2/ErbB3 signalling protects human trophoblasts against apoptosis to preserve differentiationSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.