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Genotype and phenotype landscape of MEN2 in 554 medullary thyroid cancer patients: the BrasMEN study

13 Feb 2019

Abstract excerpt

Multiple endocrine neoplasia type 2 (MEN2) is an autosomal dominant genetic disease caused by RET gene germline mutations that is characterized by medullary thyroid carcinoma (MTC) associated with other endocrine tumors. Several reports have demonstrated that the RET mutation profile may vary according to the geographical area. In this study, we collected clinical and molecular data from 554 patients with...

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PMID: 30763276
DOI: 10.1530/ec-18-0506

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