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Metabolic Adaptation in Methicillin-Resistant Staphylococcus aureus Pneumonia

11 Feb 2019

Abstract excerpt

Abstract Methicillin-resistant Staphylococcus aureus (MRSA) is a versatile human pathogen that is associated with diverse types of infections ranging from benign colonization to sepsis. We postulated that MRSA must undergo specific genotypic and phenotypic changes to cause chronic pulmonary disease. We investigated how MRSA adapts to the human airway to establish chronic infection, as occurs during cystic...

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PMID: 30742488
DOI: 10.1165/rcmb.2018-0389oc

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