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Peripheral Blood Mononuclear Cells Demonstrate Mitochondrial Damage Clearance During Sepsis

9 Feb 2019

Abstract excerpt

OBJECTIVES: Metabolic derangements in sepsis stem from mitochondrial injury and contribute significantly to organ failure and mortality; however, little is known about mitochondrial recovery in human sepsis. We sought to test markers of mitochondrial injury and recovery (mitochondrial biogenesis) noninvasively in peripheral blood mononuclear cells from patients with sepsis and correlate serial measurements with...

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PMID: 30730439
DOI: 10.1097/ccm.0000000000003681

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