Article
Molecular profiling of adult acute myeloid and lymphoid leukemia in a major referral center in Lebanon: a 10-year experience report and review of the literature.
Molecular biology reports - 1 Apr 2019
Assaf Nada, El-Cheikh Jean, Bazarbachi Ali, Salem Ziad, Farra Chantal, Chakhachiro Zaher, Nassif Samer, Zaatari Ghazi, Mahfouz Rami
Abstract excerpt
Recurrent genetic abnormalities confer distinct morphologic features and play a role in determining the clinical behavior, prognosis and adequate treatment of acute leukemia. In the MENA region, only one study targets the frequency of genetic modifications in AML, reporting a higher occurrence of acute promyelocytic leukemia in Lebanon. Determining the frequency of translocations and gene mutations in acute...
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