Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

ALPS-Like Phenotype Caused by ADA2 Deficiency Rescued by Allogeneic Hematopoietic Stem Cell Transplantation

14 Jan 2019

Abstract excerpt

. The disease has a wide clinical spectrum encompassing early-onset vasculopathy (targeting skin, gut and central nervous system), recurrent fever, immunodeficiency and bone marrow dysfunction. Different therapeutic options have been proposed in literature, but only steroids and anti-cytokine monoclonal antibodies (such as tumor necrosis factor inhibitor) proved to be effective. If a suitable donor is available,...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Blood disorders and treatments
Share to Cytomegalovirus and herpesvirus research
Share to Immunodeficiency and Autoimmune Disorders

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 30692987
DOI: 10.3389/fimmu.2018.02767

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

ALPS-Like Phenotype Caused by ADA2 Deficiency Rescued by Allogeneic Hematopoietic Stem Cell TransplantationPMID 30692987Read ↗

Novel Adenosine Deaminase 2 (ADA2) Mutations Associated With Hematological Manifestations.Semantic proximity Read ↗

Clinical, immunological, and genetic features in 780 patients with autoimmune lymphoproliferative syndrome (ALPS) and ALPS-like diseases: A systematic review.Semantic proximity Read ↗

Autoimmune Lymphoproliferative Syndrome (Alps) Disease and Alps Phenotype: Are They Two Distinct Entities?Semantic proximity Read ↗

Deficiency of Adenosine Deaminase 2 (DADA2): Updates on the Phenotype, Genetics, Pathogenesis, and Treatment.Semantic proximity Read ↗

Autoimmune Lymphoproliferative Syndrome (ALPS) Disease and ALPS Phenotype: Are They Two Distinct Entities?Semantic proximity Read ↗

FADD Deficiency Mimicking ALPS-FAS: An Expanding Phenotype.Semantic proximity Read ↗

ALPS, FAS, and beyond: from inborn errors of immunity to acquired immunodeficiencies.Semantic proximity Read ↗

The Many Faces of a Monogenic Autoinflammatory Disease: Adenosine Deaminase 2 Deficiency.Semantic proximity Read ↗

Advances in autoimmune lymphoproliferative syndromes.Semantic proximity Read ↗

[Multiple facets of ADA2 deficiency: Vasculitis, auto-inflammatory disease and immunodeficiency: A literature review of 135 cases from literature].Semantic proximity Read ↗

Hematopoietic stem cell transplantation rescues the hematological, immunological, and vascular phenotype in DADA2.Semantic proximity Read ↗

A Monogenic Disease with a Variety of Phenotypes: Deficiency of Adenosine Deaminase 2Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.