Article
Natural killer cells for cancer immunotherapy: a new CAR is catching up
1 Jan 2019
Abstract excerpt
Immunotherapy has revolutionised cancer treatment. Since the approval of ipilimumab (an anti-cytotoxic T lymphocyte antigen [CTLA]-4 monoclonal antibody) in 2011 for the treatment of patients with malignant melanoma, immune checkpoint inhibitors such as anti-PD-1, anti-PD-L1, and anti-CTLA-4 have demonstrated their power in the clinic to treat previously untreatable terminal tumours. These success stories finally...
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