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Article

Deficiency of TPPP2, a factor linked to oligoasthenozoospermia, causes subfertility in male mice

24 Jan 2019

Abstract excerpt

Abstract Oligoasthenozoospermia is a major cause of male infertility; however, its etiology and pathogenesis are unclear and may be associated with specific gene abnormalities. This study focused on Tppp2 (tubulin polymerization promoting protein family member 2), whose encoded protein localizes in elongating spermatids at stages IV‐VIII of the seminiferous epithelial cycle in testis and in mature sperm in the...

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PMID: 30680919
DOI: 10.1111/jcmm.14149

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