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Article

Differential modulation and prognostic values of immune-escape genes in uveal melanoma

17 Jan 2019

Abstract excerpt

Uveal melanoma (UM) is the most common primary intraocular cancer in adults. In the present study, we aimed to characterize the immunological features of primary UM cancer and to provide an association with prognostic markers and outcome. Also, we assessed the influence of the microenvironment on the expression of inhibitory immune checkpoints in UM. Genes of interest included MHC Class I and Class II molecules,...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 30653520
DOI: 10.1371/journal.pone.0210276

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