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The relationship between microRNAs and Rab family GTPases in human cancers

4 Jan 2019

Abstract excerpt

microRNAs (miRNAs), as a group of noncoding RNAs, posttranscriptionally control gene expression by binding to 3'-untranslated region (3'-UTR). Ras-associated binding (Rab) proteins function as molecular switches for regulating vesicular transport, which mainly have oncogenic roles in cancer development and preventing the efficacy of chemotherapies. Increased evidence supported that miRNAs/Rabs interaction have...

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PMID: 30609026
DOI: 10.1002/jcp.28038

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