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Cyclin-dependent kinase 9 (CDK9) is a novel prognostic marker and therapeutic target in osteosarcoma

20 Dec 2018

Abstract excerpt

BACKGROUND: Cyclin-dependent protein kinase 9 (CDK9) has been shown to play an important role in the pathogenesis of malignant tumors. However, the expression and function of CDK9 remain unknown in osteosarcomas. The purpose of this study is to assess the expression, function and clinical prognostic relationship of CDK9 in osteosarcomas. METHODS: A tissue microarray of 70 patient specimens was analyzed by...

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PMID: 30579871
DOI: 10.1016/j.ebiom.2018.12.022

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