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Article

Mapping of H3N2 influenza antigenic evolution in China reveals a strategy for vaccine strain recommendation.

Nature communications - 28 Feb 2012

Du Xiangjun, Dong Libo, Lan Yu, Peng Yousong, Wu Aiping, Zhang Ye, Huang Weijuan, Wang Dayan, Wang Min, Guo Yuanji, Shu Yuelong, Jiang Taijiao

Abstract excerpt

One of the primary efforts in influenza vaccine strain recommendation is to monitor through gene sequencing the viral surface protein haemagglutinin (HA) variants that lead to viral antigenic changes. Here we have developed a computational method, denoted as PREDAC, to predict antigenic clusters of influenza A (H3N2) viruses with high accuracy from viral HA sequences. Application of PREDAC to large-scale HA...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Hemagglutinin Glycoproteins, Influenza Virus

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Source

Identifiers

PMID: 22426230
DOI: 10.1038/ncomms1710

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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