Article
Effect of interaction between outer membrane permeability and beta-lactamase production on resistance to beta-lactam agents in gram-negative bacteria.
Reviews of infectious diseases - 1 Jan 2000
Sawai T, Yamaguchi A, Hiruma R
Abstract excerpt
The effect of the interaction of beta-lactamase production and outer membrane permeability on the bacterial resistance to beta-lactam antibiotics was investigated using the Escherichia coli K12 substrains, which have outer membrane mutation and produce TEM-type penicillinase. Experiments confirme...
Topics
- Anti-Bacterial Agents
- Cell Membrane Permeability
- Drug Resistance, Microbial
- Escherichia coli
- Gram-Negative Bacteria
- Hydrolysis
- Mutation
- R Factors
- beta-Lactamases
- beta-Lactams