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Article

miR-342-5p as a Potential Regulator of HER2 Breast Cancer Cell Growth

7 Dec 2018

Abstract excerpt

BACKGROUND: HER2 positive Breast Cancers (BC) have aggressive behavior and poor prognosis. Previously, we have identified miR-342-5p as an upstream regulator of HER2 signaling, as well as inhibitor of HER2 positive BC cell line growth. OBJECTIVE: Here, we aimed to further investigate the molecular mechanisms behind miR-342-5pinduced HER2 pathway deregulation. METHOD: Two HER2 amplified breast cancer cell lines...

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PMID: 30520388
DOI: 10.2174/2211536608666181206124922

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