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Article

The fluid membrane determines mechanics of erythrocyte extracellular vesicles and is softened in hereditary spherocytosis

19 Nov 2018

Abstract excerpt

Abstract Extracellular vesicles (EVs) are widely studied regarding their role in cell-to-cell communication and disease, as well as for applications as biomarkers or drug delivery vehicles. EVs contain membrane and intraluminal proteins, affecting their structure and thereby likely their functioning. Here, we use atomic force microscopy for mechanical characterization of erythrocyte, or red blood cell (RBC), EVs...

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Share to Erythrocyte Function and Pathophysiology
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PMID: 30470753
DOI: 10.1038/s41467-018-07445-x

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