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A large HCV transmission network enabled a fast-growing HIV outbreak in rural Indiana, 2015

1 Nov 2018

Abstract excerpt

BACKGROUND: A high prevalence (92.3%) of hepatitis C virus (HCV) co-infection among HIV patients identified during a large HIV outbreak associated with injection of oxymorphone in Indiana prompted genetic analysis of HCV strains. METHODS: Molecular epidemiological analysis of HCV-positive samples included genotyping, sampling intra-host HVR1 variants by next-generation sequencing (NGS) and constructing...

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PMID: 30448155
DOI: 10.1016/j.ebiom.2018.10.007

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