Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

TIM-1 Ubiquitination Mediates Dengue Virus Entry

1 May 2018

Abstract excerpt

Dengue virus (DENV) is a major human pathogen causing millions of infections yearly. Despite intensive investigations, a DENV receptor that directly participates in virus internalization has not yet been characterized. Here, we report that the phosphatidylserine receptor TIM-1 is an authentic DENV entry receptor that plays an active role in virus endocytosis. Genetic ablation of TIM-1 strongly impaired DENV...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Complement system in diseases
Share to Mosquito-borne diseases and control
Share to Phagocytosis and Immune Regulation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 29742433
DOI: 10.1016/j.celrep.2018.04.013

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

TIM-1 Ubiquitination Mediates Dengue Virus EntryPMID 29742433Read ↗

TIM-family Proteins Promote Infection of Multiple Enveloped Viruses through Virion-associated PhosphatidylserineSemantic proximity Read ↗

The Phosphatidylserine and Phosphatidylethanolamine Receptor CD300a Binds Dengue Virus and Enhances InfectionSemantic proximity Read ↗

The TIM and TAM Families of Phosphatidylserine Receptors Mediate Dengue Virus EntrySemantic proximity Read ↗

TIM-1 Promotes Japanese Encephalitis Virus Entry and InfectionSemantic proximity Read ↗

Receptors and routes of dengue virus entry into the host cellsSemantic proximity Read ↗

Hijacking the Host Immune Cells by Dengue Virus: Molecular Interplay of Receptors and Dengue Virus EnvelopeSemantic proximity Read ↗

TIM-1 acts a dual-attachment receptor for Ebolavirus by interacting directly with viral GP and the PS on the viral envelopeSemantic proximity Read ↗

Viral Interactions with Adaptor-Protein Complexes: A Ubiquitous Trait among Viral SpeciesSemantic proximity Read ↗

TIM-1 serves as a receptor for Ebola virus in vivo, enhancing viremia and pathogenesisSemantic proximity Read ↗

Dissecting the Cell Entry Pathway of Dengue Virus by Single-Particle Tracking in Living CellsSemantic proximity Read ↗

Beyond the Surface: Endocytosis of Mosquito-Borne FlavivirusesSemantic proximity Read ↗

Dengue virus reduces expression of low-density lipoprotein receptor-related protein 1 to facilitate replication in Aedes aegyptiSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.