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Article

MicroRNA 27b-3p Modulates SYK in Pediatric Asthma Induced by Dust Mites

22 Oct 2018

Abstract excerpt

The PI3K-AKT pathway is known to regulate cytokines in dust mite-induced pediatric asthma. However, the underlying molecular steps involved are not clear. In order to clarify further the molecular steps, this study investigated the expression of certain genes and the involvement of miRNAs in the PI3K-AKT pathway, which might affect the resultant cytokine-secretion. In-vivo and in-vitro ELISA, qRT-PCR and...

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PMID: 30406061
DOI: 10.3389/fped.2018.00301

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