Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Dual-center, dual-platform microRNA profiling identifies potential plasma biomarkers of adult temporal lobe epilepsy

2 Nov 2018

Abstract excerpt

BACKGROUND: There are no blood-based molecular biomarkers of temporal lobe epilepsy (TLE) to support clinical diagnosis. MicroRNAs are short noncoding RNAs with strong biomarker potential due to their cell-specific expression, mechanistic links to brain excitability, and stable detection in biofluids. Altered levels of circulating microRNAs have been reported in human epilepsy, but most studies collected samples...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Epilepsy research and treatment
Share to Glioma Diagnosis and Treatment
Share to MicroRNA in disease regulation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 30396857
DOI: 10.1016/j.ebiom.2018.10.068

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Dual-center, dual-platform microRNA profiling identifies potential plasma biomarkers of adult temporal lobe epilepsyPMID 30396857Read ↗

Serum MicroRNAs as Predictors of Diagnosis and Drug-resistance in Temporal Lobe Epilepsy: A Preliminary StudySemantic proximity Read ↗

Brain cell-specific origin of circulating microRNA biomarkers in experimental temporal lobe epilepsySemantic proximity Read ↗

Expression and Potential Function of Plasma Exosomal microRNAs (miR-483-5p, miR-671-5p, and miR-150-3p) in a Mouse Mode and in Mesial Temporal Lobe Epilepsy PatientsSemantic proximity Read ↗

MicroRNAs in epilepsy: pathophysiology and clinical utilitySemantic proximity Read ↗

Systematic review and meta-analysis of differentially expressed miRNAs in experimental and human temporal lobe epilepsy.Semantic proximity Read ↗

Circulating microRNAs as potential biomarkers for genetic generalized epilepsies: a three microRNA panelSemantic proximity Read ↗

Expression of microRNA-129-2-3p and microRNA-935 in plasma and brain tissue of human refractory epilepsySemantic proximity Read ↗

Circulating miRNAs expression profiling in drug-resistant epilepsy: Up-regulation of miR-301a-3p in a case of sudden unexpected deathSemantic proximity Read ↗

Circulating microRNAs and isomiRs as biomarkers for the initial insult and epileptogenesis in four experimental epilepsy models: The EPITARGET studySemantic proximity Read ↗

Identification of miRNAs in extracellular vesicles as potential diagnostic markers for pediatric epilepsy and drug-resistant epilepsy via bioinformatics analysisSemantic proximity Read ↗

A super-series of extracellular miRNA in cerebrospinal fluid reveals broad patterns associated with neurologic diseaseSemantic proximity Read ↗

Early Detection of Temporal Lobe Epilepsy: Identification of Novel Candidate Genes and Potential Biomarkers Using Integrative Genomics AnalysisSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.