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Article

Circulating microRNAs as potential biomarkers for genetic generalized epilepsies: a three microRNA panel

20 Nov 2019

Abstract excerpt

BACKGROUND AND PURPOSE: Genetic generalized epilepsies (GGEs) encompass a group of syndromes of mainly genetic causes, characterized by the involvement of both hemispheres. MicroRNAs (miRNAs) are small non-coding RNAs with a critical role in the regulation of neuronal biological processes through gene expression modulation. Dysregulated miRNA expression has been shown in epilepsy. Due to their stability in...

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PMID: 31746515
DOI: 10.1111/ene.14129

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