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Modelling of Cellular Survival Following Radiation-Induced DNA Double-Strand Breaks

26 Oct 2018

Abstract excerpt

A mechanistic model of cellular survival following radiation-induced DNA double-strand breaks (DSBs) was proposed in this study. DSBs were assumed as the initial lesions in the DNA of the cell nucleus induced by ionizing radiation. The non-homologous end-joining (NHEJ) pathway was considered as the domain pathway of DSB repair in mammalian cells. The model was proposed to predict the relationship between...

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PMID: 30385845
DOI: 10.1038/s41598-018-34159-3

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