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Targeting quorum sensing for manipulation of commensal microbiota

18 Dec 2024

Abstract excerpt

Bacteria communicate through the accumulation of autoinducer (AI) molecules that regulate gene expression at critical densities in a process called quorum sensing (QS). Extensive work using simple systems and single strains of bacteria have revealed a role for QS in the regulation of virulence factors and biofilm formation; however, less is known about QS dynamics among communities, especially in vivo. In this...

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PMID: 39696328
DOI: 10.1186/s12896-024-00937-3

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