Glycan Microarray-Assisted Identification of IgG Subclass Targets in Schistosomiasis

Abstract excerpt

Infection with schistosomes is accompanied by the induction of antibodies against the parasite. Despite having IgG against both protein and glycan antigens, infected individuals remain chronically infected for many years, or until treated, and re-infection is common in endemic areas due as immunity does not develop effectively. Parasite specific IgG subclasses may differ in functionality and effectivity with...

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