Article
Genome-wide significant regions in 43 Utah high-risk families implicate multiple genes involved in risk for completed suicide.
Molecular psychiatry - 1 Nov 2020
Coon Hilary, Darlington Todd M, DiBlasi Emily, Callor W Brandon, Ferris Elliott, Fraser Alison, Yu Zhe, William Nancy, Das Sujan C, Crowell Sheila E, Chen Danli, Anderson John S, Klein Michael, Jerominski Leslie, Cannon Dale, Shabalin Andrey, Docherty Anna, Williams Megan, Smith Ken R, Keeshin Brooks, Bakian Amanda V, Christensen Erik, Li Qingqin S, Camp Nicola J, Gray Douglas
Abstract excerpt
Suicide is the 10th leading cause of death in the United States. Although environment has undeniable impact, evidence suggests that genetic factors play a significant role in completed suicide. We linked a resource of ~ 4500 DNA samples from completed suicides obtained from the Utah Medical Examiner to genealogical records and medical records data available on over eight million individuals. This linking has...
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