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Drug Target Prioritization for Alzheimer's Disease Using Protein Interaction Network Analysis

1 Oct 2018

Abstract excerpt

Alzheimer's disease (AD) is an age-related neurodegenerative disorder that accounts for numerous deaths worldwide. AD is the most common cause of dementia, characterized by accumulation of fibrous amyloid beta protein in the brain with clinical symptoms, such as loss of intellectual and social skills, gradually leading to the death of brain cells. The genetic complexity of AD during disease progression requires a...

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PMID: 30346884
DOI: 10.1089/omi.2018.0131

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