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Recent Applications of Bioinformatics in Target Identification and Drug Discovery for Alzheimer’s Disease

1 Oct 2022

Abstract excerpt

Alzheimer's disease (AD) is a complex multifactorial neurodegenerative disease characterized by progressive memory loss. The main pathological features of the disease are extracellular deposition of amyloid β (Aβ) plaques and intracellular neurofibrillary tangles composed of hyperphosphorylated tau protein. Understanding factors contributing to AD progression, the number of molecular signatures, and the...

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PMID: 36305125
DOI: 10.2174/1568026623666221026091010

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